Bp (Edmonton, Ab, Canada) on 09/17/2011
I've been suffering with depression and numerous physical problems for several years, to the point of being nearly bedridden at times, and being unable to function productively more days than not. I've tried dozens and dozens of natural remedies, with only limited effect.
When I began taking the methylene blue, I had a couple of days of discomfort in the area of one kidney. But within a couple of days, this had subsided, and I currently have the strongest physical and mental health I've had in years! My mood is joyful, and I have much improved focus when reading. The pains in my spleen area have virtually disappeared, I can breath comfortably at rest (my breathing was laboured before), and I have gone from needing 9 or 10 hours of sleep a night to needing only 6 or 7 to get by comfortably.
MB isn't a cure-all -- I still have back problems, and skin issues, and some other symptoms from congenital/genetic issues. But, based on my own experience, I recommend trying it if you have had problems with candida or parasites, anything spleen-related, depression without obvious cause, persistent breathing problems, or thyroid/glandular disfunction.
I dilute one drop of the pet-store MB into four litres of water (two full 2-litre pop-bottles), and take between a half-cup and a full cup, with extra water added to further dilute the dose, once or twice daily. Since MB is used to disinfect standing water, it shouldn't need to be refrigerated, either.
Replied By Bp (Edmonton, Ab, Canada) on 11/13/2011
Replied By Heather (San Diego, Ca) on 03/08/2013
After a week on MB, I noticed the abdominal area cysts hadn't been bothering me, so I began pressing on all the parts that hurt, and no pain. I'm assuming they are now cleared up. Note that two weeks prior to MB, I finally took a course of antibiotics, which may have helped, but the pain was still there, and they still hurt when I pressed on them even a week after discontinuing the antibiotics.
Other supplements I take are Lugols 5% (average 1 drop per day); daily, a half dose of a good quality, high b vitamin multi, vitamin D 1500-2000 per day, N-A-C, Milk Thistle, Lysine, 3-4 grams Vitamin C and melatonin; Zinc, selenium lithium aspartate (5 mg) are taken 3-4 x per week. Also, I've been faithfully making Ted's alkalzing formula 1/4 tsp baking soda with an acid (ACV, lemon juice, or for now, just the vitamin C crystals to take with the Methylene Blue). Additional baking soda taken on its own before bed.
Take a few low dose (usually 1/3 of lowest dose) Xanax and Trazadone for sleep or panic attacks as needed. (Once in past week.) Taking the MB in 2-5 drops, 2-3 x per day in the 0.1% solution recommended by this site (Ted). I've settled for now upon 2 drops but experimented a bit.
I've experienced reduced brain fog, increased ability to focus, recall of memories and vocabulary that were lost to the brain fog, deeper sleep, and less anxiety but not ruling out placebo effect (or the addition of Lysine) yet as I haven't been on it for months. I can only say that the cysts are not a placebo effect, as they were painful and I wasn't taking MB for them per se, although I did hope for improved general health due to possible viral/fungal/bacterial infection. I have traveled to jungles, etc. , in past and thought perhaps I picked up something US docs don't screen for.
Side effects I may be experiencing from Methylene Blue are headaches (mild, infrequent), dehydration - drinking lots more water, buzzing in brain - specifically the right side over temple, and sometimes on top of hear, stiffness in neck/ upper back. Except for the buzzing, the others may not be related at all. The brain buzzing is particulalry amplified by coffee and/or N-A-C. I've also been experiencing a buzzing in my lower legs (outside of calf) for a few days.
There's research on Methylene Blue that says it is an inhibitor of Tau protein aggregation. (From wiki: Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes.[1] When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. http://en.wikipedia.org/wiki/Tau_protein)
Melatonin also reduces tau hyperphosphorylation, at least in rat brain studies, so I'm going to taper off of melatonin (I've taken 9 grams for a year) for a while. It might somehow be related to the buzz effect too.
That's my report. I fully expect that the mental benefits from my lose dose Methylene Blue experience will be a fail/placebo, but I'm going to keep it up for two or three more months, just in case.
Replied By Roec (Los Angeles, Ca) on 03/11/2013
I have looked almost everywhere for it, in healthfood stores. No one has it. Whole Foods and Earwhone doesn't even have iodine other than the one help derived iodine and does not provide any percentages on the lable and the fluid is clear.
Replied By Heather (San Diego, Ca) on 03/14/2013
Just realized that I wrote I was taking 9 grams of melatonin. LOL! That would be an overdose for sure. I was taking 9 mgs, and have tapered down to 3 mg. Will continue tapering to 1.5 mg.
At this point, the brain buzzing has become barely noticeable on top of my head. That buzzing sensation in the legs and right side have stopped as well (those are areas that flared up with buzzing and pain once when I took doxycycline -so it's interesting to note) and it appears the other possible side effects - back pain, headaches, weren't related. I do suspect the interaction of melatonin with methylene blue (MB) was part of the buzzing issue. Regular coffee is definitely also an isssue in the buzzing, so my advice is avoid or drink decaf.
MB has not increased my energy levels but I still think it has increased my ability to focus and has perhaps reduced depression and anxiety as well.
I don't know how many miccrograms I'm getting of the MB with each drop at 0.1%. I think it could be 60 mcg. If anyone has a guesstimate, I'd really appreciate an approximation to assist with my research on scientific studies with MB.