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Terri (Fort Myers, Florida) on 11/30/2010

I purchased a 2.303% methylene blue solution from local pet store. Instead of going through dilutions, can anyone tell me in simpler terms such as 1-2 drops in 16 oz. Water?

Replied By Self (Ny) on 11/30/2010

You could add one drop of 2.3% MB to 18 cups of water (which also equals one gallon and one pint of water) and take one cup of this twice a day. You do not want to take too much MB or it can make your mind too active. Don't forget to take 2,000 milligrams (or 2 grams) of vitamin C (sodium ascorbate) a day too.

Replied By Tom (Regina, Sk) on 11/30/2010

Terri:
I'm assuming you meant to ask "... To end up at 0.1% concentration"?
If so, then this means that you need 22 times as much water volume to dilute as the amount you're wanting to dilute, since. 1% IS 1/23 of 2.3%. The total of 1 part solution and 22 parts water will equal the total watered-down volume 23 parts. To make the math a lot easier, one can just dilute 20:1, ie 20 parts water to 1 part solution and be very close. Measurement quantities:
20 metric drops per ml
5 ml per teaspoon (Tsp)
3 Tsp per tablespoon (Tbsp)
2 tablespoons per ounce
Thus 600 drops, or 30 ml, or 6 teaspoons per ounce. 1 cup= 8 oz= 4800 drops= 240 ml= 48 Tsp= 16 Tbsp

So there it is. Using the 20 ratio for dilution, to get 1 cup watered down solution, just dilute 240/20= 12 ml of 2. 3% (just use a kitchen measuring spoon of 1 Tsp= 5ml) INTO the 1 cup of water.

Replied By Claudia (Calgary, Alberta , Canada) on 12/21/2010

I got my methylene blue from the pharmacy. The pharmacist had absolutely no idea how to provide a 0.1% solution, so what I have now is 50mg/ml. Does anyone have any idea how to convert this? TIA.

Replied By Amazinggrace (Yucca Valley, Ca) on 02/08/2011

I don't have metric measuring instruments, so to get a 1:22 ratio, I used one Tablespoon of methylene blue and 22 Tablespoons of water. 22 Tablespoons equals 1 and a quarter cups plus 2 Tablespoons. (Derived from 16 T. = 1 Cup)

Replied By Randy (Myrtle Beach, Sc) on 01/09/2012

Does anyone know how many drops of the diluted. 1% of the MB one would have to take for it to have an MAOI effect?

Also, would anyone know what the conversion would equate to of X amount of drops of. 1% solution of MB to X amount of mcg's or mg's of MB?

Replied By Randy (Myrtle Beach, Sc) on 01/10/2012

I also should have added to my post about that I do know that MB can have MAOI properties but I do not know if it has those properties at the suggested drops of. 1% solution of anywhere between 3-8 drops on this site that is suggested. I think it would be wise if anyone could determine how many drops it would take at the. 1% solution to have MAOI effects.

Maybe Ted could weigh in on this. Reason being, if someone were to ridiculously experiment with many more drops and get in the range of it acting as an MAOI, then it is dangerous to do so if in particular that you are taking it along with an SSRI antidepressant.

To be on the safe side might as well include if taken with an NRI as well. Do your own web research to confirm this. I do take MB for added energy but I also take more drops than 8 with no adverse effects. I'm not recommending anyone else take more than 8. Everyone is different... Plus I also am not on any antidepressant. Just a word of caution here if anyone is unaware of the MAOI effects of MB and not to mix with AD's if in fact you are getting in range with the drops to have it act as an MAOI.

Replied By David (Nerja, Malaga/spain) on 10/25/2012

I have 100mg MB powder. Do anyone know how to much 0.1 solution this will make? Do I just mix 1ml with 1l water?

Replied By J.park (Cerritos, Ca) on 02/19/2017

I'm new to this site, so I just saw your message very late & realized that, as I said above in my writing, there is quite a confusion in % of MB.

You can calculate the percentage stuff using the same formula: % = g/cc -> cc = g/%:

Since you know g=0.1(100mg), %=0.001,

cc = g/% = 0.1/0.001 = 100.

So you'd make 100cc(mL) of 0.1% solution of MB.

Warning: in above formula 'g' must be in grams and % must be in "fraction" as the calculation shows.

Replied By J.park (Cerritos, Ca) on 02/19/2017

Maybe I didn't make it clear in my previous writing,

you just put the 100mg MB into a graduated container and add distilled water to fill up to 100cc(mL), the total volume is to be 100cc when completely dissolved (which include MB & water of course).

Replied By Richard (uk) on 04/03/2023
Thought I'd try it, sounds straightforward, except I've ordered from eBay £5 for 40grammes China with 98.5 % purity. Is this the right stuff? I did leave them a question about it. where to obtain ups, just run that gram dilution again, from above, then 10 drops in morning, seems contraindicated to take in the evening🤔

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