Replied By Bee (Anon, Anon) on 03/15/2010
If you do take 5-HTP and Zoloft, there is a chance that your serotonin levels will rise too high. Also, realize that there is a chance of withdrawal as you wean yourself off of Zoloft. I would consult with a medical professional to help you wean off the Zoloft gradually, to ease any withdrawal. I used 5-htp to help wean off Paxil(another SSRI)- I'm at a half dose now, but not trying to reduce it any right now. I had really severe withdrawal so it may be better to give your system a break before starting the 5-htp. At least in my experience weaning off is really hard and it's important to take care of yourself and have the support of someone to help you get through it.Replied By Kimbies (Omaha, Nebraska) on 03/26/2010
regarding the question of taking 5HTP with Zoloft. As long as you have a window of over 8-10 hours between taking the Zoloft and 5HTP it should not be a problem. Many people successfully are on both just not at the same time in the day as to avoid Seratonin overload.Replied By Shelby (Wilmington, Ca) on 12/22/2011
Jaime! You should look into meditation and yoga to help with your depression. Sending you lots of love and light :)