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Len ( Las Vegas, NV) on 07/10/2009

Can someone tell me the difference between L-carnitine and acetyl-l-carnitine? I see there's a big difference in price. When clicking on L-carnitine under the supplements section here (on EC) I see people are talking about both as if they are one in the same and I know there not. Thanks-Len
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Replied By Luis (Cali, Colombia) on 07/11/2009

Dear Len:

Briefly, L-Carnitine is for heart, Acethyl-L-Carnitine is for brain.

To your best days.

Luis

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Replied By Becky (La Porte, Texas) on 06/05/2013

I do not understand why L-Carnitine is recommended by some you, to take on an empty stomach. I have tried that, and it makes me very nauseated. So I am definitely eating something first. What are the benefits of taking on empty stomach?
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Replied By Lindseynarrates (Atlanta, Georgia, Usa) on 03/04/2014

It is because of two reasons: Firstly, as with basically ALL free-form amino-acids, you are taking it for a specific reason, and need it more than the other amino-acids, and if you eat something that contains a large amount of OTHER amino-acids, it will absolutely compete for absorption. Secondly, as with basically all vitamin, mineral, herb, and amino-acid supplements, absorption is significantly enhanced when taken WITHOUT food, with several exceptions of course, but we are talking about acetyl l-carnitine.

HOWEVER...and this is VERY important: It is very advisable to eat SOMETHING that contains a decent amount of carbohydrates, especially glucose, because acetyl l-carnitine, especially when coupled with ALA--alpha lipoic acid--drastically and rapidly lower blood-sugar, and I actually had a very severe hypoglycemic-attack about six days ago because I took a "rather" large dose of ALA and acetyl l-carnitine on a fully empty stomach, and had not eaten for about 10 hours, or so.

Lindsey

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