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John (San Francisco, CA) on 02/26/2009
5 out of 5 stars

I'd like to give a cautionary thumbs-up for Grapefruit Seed Extract (GSE) as a potential remedy for acute and/or chronic sinustitis, and I'd like to continue posting my progress as i'm just beginning this treatment. First, a little history (maybe this will sound familiar to some).

I'm a 41-year-old male in otherwise excellent health who has had repeated sinus problems and infections since 1994. In march 2007 I began to have a series of R-side sinus infections (one was a particularly painful sphenoid sinus infection confirmed my a CT scan).

During this time I did frequently use a neti pot with NeilMed salt packs. It did help to clear and open my sinuses, but there was always one pocket of inflammation that was chronic, that never seemed to heal completely. My infections would always start there, where it seemed that once the inflammation in that pocket reached a certain point, that bacteria would become trapped, and within 5 days I'd have another bacterial infection that would require another round of antibiotics.

By september 2007 my ENT doc said if i got infected again, we'd have to have a serious look at surgery (and for the sphenoid, it is a very delicate procedure as it's located near the base of the skull with a host of delicate nerves and arteries that run along it's walls).

When the next infection began to take hold that september, I decided to take see a well-respected accupuncturist/Traditional Chinese Medicaine doc. The treatment consisted of accupuncture and cooking down chinese herbs that I'd have to drink twice a day. The accupuncture does provide near-immediate relief. I could go from a state of feeling the typical fever/chills and sinus pain from that pocket becoming infected, to having it open up deeply and drain/recover within 2 hours. The herbs evidently helped to reduce inflammation and keep it open, as well as boost my immune system to fight off whatever may be the underlying bacteria/virus/fungus that causes this to begin with.

I have maintained with the accupuncture and herbs until now, but at a tremendous dollar cost, and still have not resolved that ever-persistent inflammed pocket in my R-sinus that is the source of all my infections. (note also that a repeat CT a few months ago showed no underlying blockages or malformations in my sinuses).

A few days ago I could feel the pocket become inflammed again and was on the road to another infection. I found this site and have pretty much been throwing the kitchen sink at it - Oil pulling with sesame oil and oil of oregano, sinus flush with hydrogen peroxide and saline H2O, ACV, and tomato tea (yummy stuff, good temporary clearing!). It kept things at bay, but could not keep that pocket open.

Today I began using GSE as a spray. I took a used antihistamine spray bottle, added a pinch or two of NeilMed salt solition, 8 drops of GSE, and water, and sprayed it in my R-nostril. It stinged a little bit in unaffected areas, but BURNED in the pocket with the inflammation. The burning eased up within minutes, but that pocket opened right up, and i could feel that it was moist and draining easily. I must state that typically the only thing that reliably opened up that pocket was accupuncture, so the fact that this simple remedy did the trick was for me very remarkable.

I continued to spray today once or twice when i felt it was drying up or when it felt it was closing up again, typically every hour or two. I had to dilute the original mixture because it felt a bit too strong, doing more than just keeping it open, but producing copious amounts of clear mucous and sneezing. One thing I noticed about other remedies to open up the sinuses (H2O2 especially) was that while it would open things up, there would be almost a reflex backlash of swelling afterward at some point.

It is my hope that by keeping up with this routine, that the GSE spray will keep the pocket open and allow it to drain and heal, and that whatever is creating the inflammation that is the precursor to my infections (be it bacterial/viral/fungal) will evenually be killed off by the GSE.

Forgive the lenghty post, but I wanted to be thorough. I will keep you posted. My hope is that if it works for me, that it may work for you as well, and we all save thousands of dollars in treating and healing the root of the problem, as opposed to just being in a maintenance mode where we are constantly treating symptoms and not the cause.

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Replied By John Hoecker (San Francisco, CA) on 03/04/2009

I'd just like to follow up regarding my use of nasal GSE spray for my chronic sinus condition after having been using it for 1 week.

I'm using 3 drops of GSE in a saline solution using a spray bottle. The "pocket" in my sinuses continues to remain open and is moist and draining, which is so important in my eyes - when that pocket closes up, it's typically only a matter of time before i get the standard infection. It has never remained open for this long.

I still do feel inflammation, but i accept that as part of the healing process. After 15 years of infections, I don't expect a 1 week cure. But i have to say that keeping that pocket open is the key to me not getting infected to begin with!

Thumbs up for GSE! Now, what to due about keeping the inflammation down and enhancing the healing??

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Replied By Glenys (Wellington, New Zealand) on 03/30/2009

To John Hoecker: Your story is familiar to me. I agree about the backlash from H2O2. I will go get some GSE. Would love an update on what's happening with you.
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Replied By Rob (Manhattan, New York) on 04/05/2009

Thanks John for your detailed account! I too have noticed a "backlash" with H202, in that it works initially but seems to irritate the tissue and cause re-inflammation. Whether in the ear or sinus. Perhaps it is to strong for some. I will try the GSE.
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Replied By Joyce (Joelton, Tn) on 04/07/2009

Hello John, Usually it is an allergy or intolerance causing the blockage and the blockage causes the infection. Try leaving off all hair sprays, after shaves, colognes, paint fumes, etc. & avoiding all of the above on other people as much as possible and see if it helps to keep your nose/sinuses open. I used to work with a guy who had surgery on his sinuses (2 times that I know of & may have had some before I met him). Poor guy, he always smelled like he had marinated himself in some strong smelling aftershave &/or cologne, but he was averse to leaving his smelly stuff off, when I suggested that it might be the cause of his chronic sinus problems.
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Replied By John (San Francisco, CA) on 07/20/2009

Hey Folks, just a follow-up on my GSE treatment and how I've adapted it...

I actually lapsed on the GSE spray in April while out of the country and got infected again unfortunately. For the last 3 months I've been using a neti pot, salt (equivalent to a NeilMed packet), about 1 tsp of Hydrogen Persoxide, and just two drops of GSE. While i haven't gotten reinfected, I've come close, in which case i bump up the amount of H2O2 and GSE, and that seems to keep it at bay.

However, I still have significant nasal inflammation in the area (and have for years), and if it closes up, infection typically follows. The GSE rinses and sprays don't seem to help with the inflammation.

As i have been on antibiotics so frequently in the last 2 years, I began to suspect a yeast and/or fungal infection was playing a role. To that end, I've limited my dairy and wheat intake, am taking a broad-spectrum probiotic, and really examine my foods for high-fructose corn syrup (aside from feeding the yeast in the belly, HFCS stimulates a major insulin response, not healthy for various reasons).

I've actually switched my GSE nasal rinse regimen and began trying colloidal silver spray and nasal rinse. From what I've studied, the colloidal silver basically interrupts the process of fungus/yeast from being able to take in O2, and dies off. I simply bought 250ppm colloidal silver solution, put about 10 drops into a nasal spray bottle, and added about 1/4 of plain tap water (er, distilled is best of course), and also about 1 tsp of colloidal silver in about 2oz tap water in a neti pot, keeping my head tilted to the side for about a minute to let it fully irrigate the sinus. From what I've read, do not put salt into the solution - it turns the colloidal silver into silver chloride, and it's the colloid form that interrupts the yeast/fungus oxygen intake. The spray is very gentle, however the rinse is uncomfortable due to being hypotonic, but that goes away within a few minutes. An alternative to salt may be to add xylitol to make the solution isotonic (equal to the particulate concentration in blood). However, there are ready-made colloidal sinus sprays available commercially.

I'm on my third day of this particular regimen. When i wake up in the morning, it is typical for me to feel stuffed up and swollen inside my nose. However, this morning i could feel my R-sinus "popping" which for me means the swollen areas are shrinking. For certain, I can tell that the inflammation is much less than normal, much more open, and I'm greatly encouraged.

Seems to me sinus maladies and treatments are very specific to the person, that there is no single bulls-eye remedy for everyone, but in my particular case this seems to be working for now. I'll report back in time and let you know what's happening.

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Replied By Sunny (Ca ) on 05/20/2015

How are you doing? It would help if you ingested the GSE. Also, the true cure is diet, your are probably allergic to many foods. Dairy, sugar, breads etc. GO raw.
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