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Joey (NY) on 02/29/2024
5 out of 5 stars

Thank you for the article. One question I have that I can't find that anyone has touched on-

Since one of the roles of statins is to "harden" existing plaque to prevent clots from breaking off, does Nattokinase work opposite of that in terms of it's power to dissolve plaque? Put another simple way, wondering if they're safe to take together or if they work against each other? Thank you.

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Replied By Art (California) on 02/29/2024

Hi Joey,

I haven't seen any studies or articles that say the two can't be taken together, but the point of the article was that nattokinase is more effective for reducing atherosclerosis than the statin drug group and it doesn't include any of the known side effects of statins, some of which could be serious as discussed here :

https://www.drugs.com/sfx/atorvastatin-side-effects.html

Art

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Replied By Sharon (MD) on 06/26/2024

Would like an answer on this topic/question. My Husband (69) has been taking 2,000 once daily of nanokinase but have since developed multiple strokes due to plaque in the brain. Really want to know this question and what natural statin he take. Thank you.
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Replied By Art (California) on 06/26/2024

Hi Sharon,

Regarding which statin for your husband to take, his doctor will make that decision for him as a prescription is required. Nattokinase, in more recent studies, have shown that 2000 mg of nattokinase is an ineffective dose for fighting atherosclerosis. The study I highlighted with over 1000 participants suggested that 10, 800 FU was useful for reducing atherosclerosis after 12 months. Here is a link to that article :

https://www.earthclinic.com/cures/high-dose-nattokinase-for-atherosclerosis.html

Here is a relevant quote from the study :

As shown in Table 5, no differences in NK efficacy were found between male and female participants, although changes in female participants were marginally greater, but were not statistically significant. We found that NK at 3, 600 FU dose was not effective in lowering lipids and suppressing atherosclerosis. Lipid levels and CCA-IMT and plaque size did not change after 12 months of NK consumption at that dose (Table 6).

Art

Replied By Jake (Chicago) on 06/27/2024

Art and Sharon,

I have been taking 12,000 NK now for the last 6 to 8 weeks. my blood pressure used to spike continually. I started Carditone and that brought it down quite substantially most of the time. I have now stopped Carditone as my blood pressure is now consistently -all the time- normal and lower - 110 to 120 over 70 or so just with the NK. No waiting anymore for the BP to normalize. Seems the Nk may be curing or at least improving the heart disease that runs in my family. (my father and his two younger brothers and the grandfather I am named after.) I am currently 80 years old.

Replied By Art (California) on 06/28/2024

Hi Jake and thank you for your feedback!

I'm very happy to hear that the high dose nattokinase is helping you significantly. In my case nattokinase had no apparent effect on my blood pressure, but it worked quite well for lowering total cholesterol, LDL, VLDL cholesterol and triglycerides while increasing my HDL cholesterol. I still maintain my blood pressure in a desirable range with Carditone.

Art

Replied By jake (chicago) on 06/29/2024

that's so interesting - your results versus mine - yet I would guess related. Aside from heart issues (family) my main issue is my kidney function - maybe that's somehow in the mix. I'm also doing well with high dose melatonin. Thanks for all your help.

Replied By Art (California) on 06/29/2024

Hi Jake,

The difference may lie in the dose you are using which is greater than the study dosage, while the dose I am taking is slightly less than the study dosage. I I haven't seen any human studies using 12, 000 FU.

Just a quick mention, a bioavailable form of magnesium such as magnesium glycinate that delivers enough actual magnesium not just magnesium glycinate to reach the RDA should be beneficial for the heart and kidneys while helping to reduce vascular calcifications.

Art


Replied By AZJJ (AZ) on 05/24/2025

I have never heard that statins harden plaque... but, IMO, statins are to be avoided, unless one has already had a heart attack and even then... VERY iffy.

Serrapeptase, nattokinase, lumbrokinase are preferable.

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