Bill (Philippines) on 06/15/2023
First, because there seems to be so much dosage confusion about MB percentage strength and number of drops used, I'm going to use a completely different quantitative method that determines how many milligrams or how many drops to supplement MB with water. There has been much of confusion over this.
But first some information that I have found to be extremely useful in helping to more fully understand the effective dosage amounts of MB needed for particular ailments :
1 drop of 1% Methylene Blue contains 0.5 mgs of MB.
1 drop of 0.1% Methylene Blue contains 0.05 mgs of MB
1 drop pf 2.33% Methylene Blue(Aquarium version ) contains 1 mg(approx.)
A half teaspoon of MB is 40 drops.
A full teaspoon of MB is 80 drops.
So armed with the above helpful definitions, I will now only describe MB dosages in milligram amounts only. Doing it this way eliminates all the confusion(and myths) of how you should use 0.1% or 1% or 2.33% MB. After all, it's the dose of MB powder in water that you supplement that is all-important -- not the percentage of MB in your dropper bottle. Right?
Ted from Bangkok has also maintained in his MB posts that supplementing the cheaper aquarium version of Methylene Blue is certainly good enough and pure enough for supplementing in humans. But if that last statement makes some readers balk in fear of "heavy metal impurites" then it's perhaps also useful to appreciate that fish live and breath in water and humans breath air. But water is a much more dense medium than air. And that means that fish are much more sensitive to poisons, heavy metals etc in their water than humans are. So if the aquarium version of MB is good enough for the more sensitive fish then it should certainly follow that aquarium MB is pure enough for us humans as well. And that's also why I've been using the aquarium version of MB, without any problems whatsoever, for over 10 years now.
Other things to remember about MB is that low MB dosages will be good enough to help give you energy and to help MB act as both an antioxidant and antimicrobial for the brain, thus helping to increase and maintain mental cognition as well as helping to prevent dementia(Alzheimer's Disease, Parkinson's Disease etc). However, much larger doses of MB will be required to kill viruses or bacteria, cure malaria, kill fungus, kill parasites, treat Methemoglobinemia, help remove blood clots etc.
But what do I mean when I say take a low dose of MB in water? -- And here is where all the confusion happens. I've read that for some people 2 drops of 1% MB(which is equivalent to 1 mg MB powder on water) is enough to fully energize them. I've also read where other people need to take as much as 16 mgs or even 100 mgs of MB(which is still a low dose for MB) to get energized. The point that I'm making here is that you will normally always have to find your own MB dose that works for you personally.
My own dose, which suits me for getting more energy and obtaining the cognitive benefits from using MB, is based on Dr Golwalkar's method that he has been using over the years to treat and cure both tuberculosis and COVID-19. He uses a teaspoon of 0.1% Methylene Blue for nebulizing(which is equivalent to 4 mgs MB powder in water) and he also recommends taking a half teaspoon of 0.1% MB orally as a sub-lingual dose(which is equivalent to taking 2 mgs MB powder in water).
My own everyday MB dose is slightly different to Dr Golwalkar's sub-lingual dose. I just add half a tablespoon of water to a small empty glass and then add 4 drops of 2.33% Methylene blue(which is equivalent to taking approximately 4 mgs of MB powder) and supplement that twice a day. But I have also taken the equivalent of more that 25 mg MB powder per day without a problem. I would also recommend using Dr Golwalker's recommendation of using 5 mls or 1 teaspoon of 0.1% MB(which is equivalent to 4 mgs MB powder in water) in a nebulizer two or three times a day when infected with COVID-19.
Some more MB facts for you. When you supplement Methylene Blue then between 75% and 80% of the MB taken orally is directly and quickly absorbed into the blood. Methylene Blue has a half-life in the human body of about 6 hours. That means that half the amount of MB that you supplemented will still be in your body after 6 hours. It's for reason of this persistence of MB in the body that I would at least advise that for low dose MB you should at least take one day off a week to reset your system and get rid of all the MB in your body.
I've also found an easy way of converting Methylene Blue from its blue oxidant form to its colorless reduced form. I will, for instance, add my 4 drops of Methylene Blue to a little water in a glass for sublingual supplementation. Then I would add a very small amount -- a tiny amount!! -- of Ascorbic Acid to the MB and walk outside and let the sunlight quickly convert the blue oxidant form of MB to it's colorless reduced form and just take it like that without giving me a blue mouth. I've also used the reduced or colorless MB form on skin problems without any blue coloring occurring. It works well and MB is also rapidly and easily absorbed into the skin.
Replied By Thomas (Germany) on 12/07/2023
EC: mgs - milligrams
Replied By Bobby (UK) on 03/06/2024
Replied By Bill (Philippines) on 03/06/2024
Hi Bobby,Methylene Blue(MB) has been used as a blue dye and as a standard treatment for malaria for over 120 years. During the Vietnam war MB powder was used by the spoonful over extended periods to help cure soldiers with malaria. For these reasons I regard MB as being quite safe to use over long periods of time.
But if you are concerned about continual use of MB, you could perhaps just use MB for 5 days a week with two days off. Or you could just take a week off after using it every month.
It's also important to ask why you are taking MB. I take MB for preventative reasons -- to aid my immune system against any unwanted, invading viruses and I also take it to help supply more oxygen to my brain to help protect my cognitive abilities.
For myself, I tend to just alternate using low dose MB with using BHT or Butylated Hydroxytoluene which also kills viruses and which is a useful anti-oxidant that acts to quench damaging free radical activity in the brain.
I'm currently considering using an MB + DMSO mix transdermally. Such a mixture could perhaps be used as an ant-viral, anti-fungal, anti-bacterial, anti-oxidant for anti-aging and as an anti-cancer treatment as well. More on that later.
Replied By Don (Wilmington NC) on 06/28/2025
I read your post and I'm also wanting to start taking MB for the same reasons you listed. I'm concerned about purchasing MB because there are so many different brands and I've read that many are not legit. Can you advise me on a reliable brand name I feel confident is not a scam?
Thanks so much
Don
Replied By Florecita (USA) on 03/07/2024
Great ideas Bill. I wonder if DMSO and MB topically would remove moles from the skin. Please do post again any results from topical application.
Replied By Brent (Australia ) on 05/28/2024
Just came across your post as I am about to start using MB for general health reasons. You mentioned moles to remove on skin I have heard that castor oil on its own or some people mix cayenne pepper with it could do the job on moles. Perhaps worth looking into out if you haven't done so already?
Replied By Bart (Columbus, Mississippi) on 10/28/2024
Put Apple Cider Vinegar on a cotton ball and hold for 15 minutes per day for 7 days. The mole will turn black a fall off. Works on any issues on your scalp.
Replied By Dee (Florida) on 07/18/2024
2 Methods
How do I mix the methylene blue solution.
The methylene Blue solution I received from Valboren Labs in Florida is in a concentrated liquid form. This should be mixed with distilled or deionized water using the recommended dosing. Dosages between 0.5 milligram per kilogram of bodyweight to 4 mg per kg. As mentioned, methylene blue is a hormetic, so low dosages have the opposite effect of high dosages. Adding 1/16th teaspoon of Ascorbic Acid to the prepared solution will facilitate better absorption and reduce the blue staining potential. After the Ascorbic Acid is added to the solution let it sit for a minimum of 3 hours before taking. With methylene blue less is more. Higher doses are not as effective a low doses (hormetic response). Dosage recommendation varies; Dr. John Lieurance suggests 0.5-1mg/kg of body weigh, t 2 to 4 days a week, with 20 to 60mg daily being therapeutic for many. Do it slowly 2 or 3 drops to start 3 times a week, and work you way up .
or
Method #2
1-2 drops am in distilled water with 1/16 tsp. of Ascordic acid first 2 days.
Increase dose on third day by 2 drops for 2 days, Continue increasing
dosage by 1 drop every 2 days, until you reach 22 drop or more. Take 6 days
in a row and 7th day off. Note: Do not take Co10 with it.
Replied By Bill (Philippines) on 07/19/2024
I prefer to take Methylene Blue(MB) according to the recommendations of Dr Deepak Golwalkar, a well known pulmonologist(lung specialist) in India. He has successfully used MB to help cure many people with tuberculosis, pneumonia and COVID-19. Dr Golwalker uses two simple protocols for COVID-19. See below.Since I prefer talking in milligram amounts rather than drops and percentages of MB please bear the following in mind because it will, hopefully, greatly simplify your own understanding of drop dosages wrt conversions in % strengths.
0.1% Methylene Blue solution contains 0.05mg MB powder per drop.
1% Methylene Blue solution contains 0.5mg MB powder per drop.
2% Methylene Blue solution contains 1.0mg MB powder per drop.
I currently regularly use Dr Golwalkar's sub-lingual MB protocol which consists of taking approximately 5 drops of 1% MB which is approximately equal to 2.5mgs MB. This is held under the tongue for at least 30 seconds and then swallowed with a little more water so that it can be directly absorbed into the blood from the stomach. And this will give you a blue tongue.
You can also use Dr Golwalkers nebulizer protocol which consists of adding 10 drops of 1%(or one teaspoon of 0.1% MB) to the water in the liquid reservoir in the nebulizer. Dr Golwalker also states that all he took in the morning before going to the hospital was MB under the tongue as described. He would always walk around the COVID-19 wards of his hospital tending his many patients without a mask. He never caught COVID-19 and the hospital he worked in never lost a patient to COVID-19 and all his patients made a FULL recovery with no LONG COVID symptoms.
I am currently using the simple sub-lingual protocol once a day(in the morning) at the moment. I find using the sub-lingual protocol on its own is a great energizer and protector at the same time. And there's really no need to use Dr Golwalker's nebulizer protocol until I'm infected with COVID-19, pneumonia or tuberculosis.
Click this link to see a previous EC post I wrote fully describing the many benefits of using MB.
Replied By Juliw (VICTORIA) on 01/19/2025
Just to clarify Bill. If the solution I have is 1% strength, do I use the undiluted drops sublingually? Also, if I have some fungal skin issues I want to treat, do I use it full strength or dilute it?Thanks for all your helpful information.
Replied By Dave (Arkansas) on 03/06/2025
I just got some MB and have started taking some. Longtime alternative and natural treatment user. I regularly take CoQ10 and I assume by 'Co10' that your are referring to CoQ10? I already took MB today and later took my usual CoQ10 before seeing your post. Can you or anyone else here let me know what is the reason to avoid CoQ10? Thanks!
Replied By Don (Wilmington NC) on 06/28/2025
Regards
Don
Replied By Ron (Atlanta) on 07/24/2025
Replied By Bill (Philippines) on 04/15/2026
But first, some history. I know, from continually reading an re-reading Ted from Bangkok's past posts on EC that he has used MB when he didn't know what disease his patient has. He also uses various other combination solutions containing humic acid, hydrogen peroxide, sodium thiosulfate and MB in dire emergencies to save the life of his patient. Therefore, wrt MB, this also means that Methylene Blue kills almost every type of pathogen out there be it virus, bacteria, fungus or small parasite. And while I was verifying that MB kills so many different pathogen species, I also discovered that methylene blue also kills mycobacterium. From Dr Deepak Golwalker's website in India -- he is a well-known pulmonologist, who has been curing patients with tuberculosis(caused by mycobacterium infection) and pneumonia since he first started using supplemented MB + nebulized MB in 1978. He also successfully treated well over 3000 COVID-19 patients at his hospital in India using his MB protocols. None of his patients died.
I also found out from Google Scholar research that MB also kills or deactivates psions(causes Creuzfeldt-Jacob disease(CJD) in cattle and humans, which is always fatal).
A while ago, I wondered whether MB could be combined with DMSO, so I researched it using the new AI search on my Firefox browser. This took me to a pharmacy research site which indeed confirmed that MB does not react with DMSO. I was happy with that.
Next, I externally applied MB + DMSO + water on several patches of eczema and other small areas of dermatitis on my skin. The MB + DMSO + water always worked and took less than a week to kill all of the dermatitis problems. I also applied this mix to a small hard lump on the back of my neck that I've had for over 20 years -- I've tried everything to get rid of it! I was worried about that lump because it was on the back of my neck near my neck bone. At one point this lump opened up and started to exude some awful smelling pus or liquid. The MB + DMSO + water combination got rid of it completely.
Here's how I prepare the MB + DMSO + water for external application and since I prefer giving the MB amount in milligrams -- here are the equivalent drop to milligram conversions for all the different percentage concentrations. See below:
0.1% MB contains 0.05 mgs per drop
1% MB contains 0.5 mgs per drop
2% MB contains 1.0 mgs per drop
From the above, you should now be able to easily work out and inter-convert the correct MB dose you need for your own preferred percentage concentration of MB.
For all external applications I use the following mix and method to make my MB + DMSO + water combination:
1. In a small shot glass, add a dropper full of DMSO.
2. Add half a dropper of water.
3. Add 4 drops of 2% MB -- or 4mgs MB -- into the shot glass and mix well.
4. Using my finger, I just dip it into the mix and apply it directly to the infected skin area.
5. Leave it alone and do not cover it. Let it all go into the skin.
6. If there is a blue stain on the treated skin -- it will go away within an hour because DMSO will pull most of the MB through the skin into the blood.
7. Apply this mix once a day for up to week. I have always had successful outcomes within about 3 or 4 days.
The DMSO will carry the MB through skin fairly rapidly thus disinfecting all skin layers and killing any pathogen in its path. This is now my go-to remedy for ALL skin problems.
Replied By Bill (Philippines) on 04/15/2026
Another Methylene Blue(MB)protocol that I use regularly is Dr Thomas Levy's oral MB protocol. His MB protocol converts the pro-oxidant MB form(stains everything blue!) to the antioxidant MB form(clear solution) -- aka Leucomethylene Blue. Leukomethylene Blue is clear and transparent -- no blue stain.Here is Dr Levy's daily protocol:
1. In a third of a glass of water, add one level teaspoon of ascorbic acid -- not ascorbate. Ascorbate doesn't work.
2. Add 5mg to 15mgs methylene blue to the glass of water.
3. Allow the glass to preferably sit in bright sunlight for 15 minutes -- this excites the MB molecules and makes it more effective.
Here is what Levy has to say about proper dosing with MB:
"For less critical patients, as well as for outpatients, oral MB dosing can range from 10 mg to 50
mg, and that dosage can be taken from one to three times daily, adjusted up or down in dose size
and frequency depending on clinical response. Even higher doses can be comfortably used for
limited times. 200 mg daily to stabilize COVID patients that are not yet critically ill is a very
reasonable dose. A reasonable regular supplementation dose can range from 5 to 15 mg daily for
general good health if there is no targeted symptom or medical condition.As a practical point regarding regular supplementation, a dose of 5 to 15 mg of 1% MB solution
(0.5 to 1.5 milliliters) can be added to a small amount of water. A teaspoon of ascorbic acid
powder (not sodium ascorbate) can then be added. After sitting for 15 minutes or less, the
solution will completely clear with just a slight residual blue tint. [129] This can then be quickly
consumed with little staining of the tongue that readily occurs with the MB solution alone.
Regardless, the staining resolves quickly. But without the added ascorbic acid, it is best to just put
the MB straight into something like tomato juice and then drink that."Source: All About Methylene Blue
In my oral MB protocol, I use 10 drops of 2% MB which works out at 10mg of MB per dose. I'm an old guy so I need more ;-)
I use MB regularly now for to help prevent dementia, for energy and for protection against viruses and infections.
Replied By Bill (Philippines) on 04/16/2026
Here is an interesting research review article that carefully explains - in plain english -- how Methylene Blue(MB) is able to disable or destroy most types of viruses in three ways:Methylene Blue Antiviral Therapy: How It May Fight Viruses
I'm using a link to a copy of that article from my Google Drive because I couldn't find the above article again when I searched for it on my browser. I guess Google has decided to "disappear" that article.
And as for all those FDA researchers insisting that you must always photodynamically prepare MB using red light, there's no need for that. That's all smoke and mirrors from the FDA to confuse our proper understanding of MB. Ted from Bangkok just used MB straight out of the bottle -- so there's absolutely no need to flood MB in red light before using it.