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Art (California) on 08/12/2022
5 out of 5 stars

The following study shows that Pumpkin Seed Oil (PSO) is useful in the treatment of Overactive Bladder (OAB), a very common health issue :

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032845/

Here is a relevant quote from the study :

>>> ' The results from our study suggest that pumpkin seed oil extracts from C. maxima as well as from C. pepo are effective for urinary disorders such as OAB in humans. ' <<<

Art

REPLY   12      

Replied By Shelly (VA) on 04/02/2023

Pumpkin seed extract has been a lifesaver!! I take 2 tablets every morning to get me thru the day, particularly at work!!
Thank you Earth Clinic😘
REPLY   10      

Replied By Art (California) on 04/02/2023

Shelly,

Thank you for the feedback to add confirmation for the effectiveness of the use of pumpkin seed extract for OAB!

Art

Replied By Frances (Cabarlah) on 02/13/2025

I wonder if eating pepitas raw would be equivalent to taking the pumpkin seed oil. Just asking for mere male.
REPLY   1      

Replied By Dano (Ontario) on 02/16/2025

According to various internet sources, 4,000 milligrams of whole pumpkin seeds is equivalent to 1,000 milligrams of pumpkin seed oil. Another comparison is or around 1.5 tablespoons of shelled pumpkin seeds which are equivalent to 400 mg pumpkin seed oil.

Replied By Debbie (Naples Florida) on 07/28/2026

I had a UTI that I tried to clear up naturally, but nothing I was trying worked. Finally, after a few weeks, I decided to take an antibiotic which helped but a few weeks after the antibiotic, I was still constantly going to the bathroom. There was no burning or bleeding, but the constant feeling of having to pee was annoying and concerning. I am so grateful that you posted the NIH study. I started taking the pumpkin seed oil and after the first dose I see an improvement. Just wanted to say thank you so much!
REPLY   5      

Replied By Art (California) on 07/28/2026

You are very welcome, Debbie and thank you for the important feedback!

I am very happy that it has offered you some relief and is starting to help so quickly to relieve your constant trips to the bathroom!

Art

Replied By Mary Lou (KY) on 09/16/2026

Art,

I am ready to start one of these regimes.

However, I'm confused.

Pumpkin seed oil and pumpkin seed extract are used interchangeably in the above posts.

They are NOT the same.

So which is it?

Replied By Art (California) on 09/16/2026

Hi Mary Lou,

You are correct, the two supplements do not have exactly the same active components. I reported on the study that used PSO extract to good effect in people with OAB, as I reported in the quote from the study :

' The results from our study suggest that pumpkin seed oil extracts from C. maxima as well as from C. pepo are effective for urinary disorders such as OAB in humans. '

EC member Shelly added her confirmation to the study results by saying PSO Extract helped her OAB also.

I don't see that anyone reported benefit from pumpkin seed oil. So I would stick to what was used in the study I reported on by using PSO Extract.

Art