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Robin (Rural, VA) on 11/15/2008

Somebody help me clear up something. I came across some L-Tryotophan 500 mg at a drug store, in a sale bin, which I understand is no longer being sold. Doing a little research, this is a typical size dosage. I had been planning on buying some 5Htp anyway. Which is generally sold in 100 mg. I keep reading that L-Tryptophan and 5Htp are the same thing. Why would there be such a vast difference in the amount of the capsules? And if they are not the same thing, someone please explain the difference.

I had also read that if you are using 5Htp to help you sleep, you have to take a lot (maybe 5) of capsules. This is not very cost effective, as a bottle of 60 would cost you about $20. I had sleep in mind when I bought the L-Tryptophan, and took one capsule. I slept like a baby. And believe me that is rare for me.

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Replied By Peggy (Loveland, Co) on 07/15/2010

My understanding is that 5-HTP is the intermediate biochemical in the body between tryptophan and serotonin. Tryptophan is in some foods like turkey and Brazil nuts, and our bodies turn it into 5-HTP, which is then turned into serotonin. L-tryptophan was the supplement version of tryptophan, but apparently had some unpleasant side effects so it was pulled. www.5-HTP.org has some good info about it. I have had good luck with 100 mg of 5-HTP on an empty stomach about an hour before bedtime. I sleep more restfully and am happier when I wake up. I understand it's good to start with 50 mg and see if that works, and add more if needed. If I run out and don't get more for a few days, I start having more insomnia and sadness within a few days. Also, it took a few days to take effect, but has been well worth it and no side effects.
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