Close

You must be logged in to love this post! Please sign in:

Close

You must be logged in to follow this post! Please sign in:

Joe (NYC, NY) on 11/02/2008
0 out of 5 stars

I have taken L-Lysine for canker sores and it worked great. I havent had one since.

If taken for a while L-Lysine can have an effect on your liver, my mistake was that i kept experimenting and supplementing on it even though i did not need it. It is good but you should pay attention to your arginine levels (consume arginine foods or supplements), as an unsafe drop in those levels can damage your liver. As in my case after consuming about 2-3 grams a day for about 3-4 months resulted in a morning with pain in my liver and a feeling as if i had a cinder block under my ribcage(i had no idea there was such a thing such as liver pain and swelling). Stopped supplementing on it, and 2 days after my liver felt way better. My cholesterol levels were also unusually high during supplementation and they went back to normal after stopping, so people should keep these things in mind, i know its easy to miss these warnings since i missed them myself. The beautiful thing about the liver though is that it can repair itself, but that doesnt mean you shouldnt be careful. Milk Thistle can help repair your liver. And if i had to do this all over again i would take L-Arginine along with L-Lysine. It would be great if someone posted these warnings in the main description for awareness so they can learn from my mistake. Thanks

REPLY   13      

Replied By Bill (Davis, CA) on 12/22/2008

One should never take as much Lysine as you have suggested. I have been taking L-Lysine for 15yrs for herpes and have never heard of such a high dose. Most medical practictioners suggest 500mg daily before food or other aminos and during an outbreak up to 1500mg/day. This has helped me control my outbreaks for a long time. Not one source that I have researched during this time has suggested such a high dose. Overloading of the liver would seem common sense with that dose.
REPLY   6      

Replied By Anthony (Canberra, Act, Australia) on 02/13/2012

Hello Bill, Continuing from your suggestion re dosage of Lysine, I am aware that Linus Pauling protocol (for heart disease) suggests high dosages ie up to 6 gms Lysine per day. This protocol also suggests Vit C of up to same quantity ie 6 gms. I have tried to research this issue but could not get answer as to What other Amino ACids to take with such high dosage of L-Lysine.

I read some where in this website, to take L-Arginine along with L-Lysine. Do you or others have any suggestions on this issue ie how much L-Arginine to take alongwith say 6 gms of L-Lysine.

EC: Can we pass this question to Ted for his expert comments please.

Anthony

EC: Forwarded to Ted, per your request.

REPLY   6      

Replied By Mmsg (Somewhere, Europe) on 02/14/2012

Anthony: I tried l-lysine numerous times for canker sores, sometimes it helped, sometimes not. I do take 1 gr. Vitamin C daily.

Then I was told to take the l-lysine away from foods. I now take one capsule of 500gr. with my morning drink as a precaution, because the CANKERS ARE GONE!!! Thank G-d! So in my experience it's not the huge amount that you might need, it's the taking it far from meals, preferably in the morning.

REPLY   5      

Replied By Anonymous (Miami, Florida) on 07/04/2013

Interesting I have been taking four caps of lysine and started having liver pain burning feeling for weeks, I read high protein diet can cause this too, it creates high acidicity and the liver doees not like this. My doctor ran tests for liver enzymes check and of course Hepatitis right away I feel kind of silly thinking that perhaps the lysine is the causative factor anyhow I stopped the Lysine right away.
REPLY   6      

Replied By Marloef8 (Comox Valley) on 01/13/2015

This is to reply to Anthony from Canberra:

Just come across an interesting article from Nutrition Review: The Collagen Connection Linus Pauling's Unified Theory of Human cardiovascular Disease that might help with your question.

REPLY   4      

Replied By Ron (Mesa) on 10/21/2015

Fighting cancer recommended is 112 grams per day.....4 oz
REPLY   5      

Replied By Speedwell (Earth) on 10/24/2015

4 ounces a day? Recommended by who, the morgue?

Lysine is definitely processed in the liver, so don't take a high dosage along with alcohol, paracetamol (Tylenol for you Yanks), or other medications processed by the liver such as metformin.

REPLY   8