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Mrs. Hill (Arkansas, US) on 06/18/2014

I have seen many posts here about DMSO. I found some that is 90% DMSO gel. When I mix it with aloe juice to get it to less than 70% solution to apply topically, it gets quite hot for several seconds. This happens less if I mix it with castor oil. I don't understand what is happening chemically.

It seems as if I have seen it said that you can't mix DMSO with other things ahead of time and must mix right before using. Is that correct? I was wanting to try DMSO and Colloidal Silver in a spray bottle for bug bites.

I appreciate your opinions. Thank you.

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Replied By Bill (San Fenando, Philippines) on 06/18/2014

Hello Mrs Hill from Arkansas...When you paint DMSO + aloe vera onto your skin it is a unique characteristic of DMSO that it will transport the aloe vera through the skin transdermally and into the blood. DMSO is able to do this by increasing the porosity or permeability of the individual skin cells which are then able to allow passage of the aloe vera through the skin cells as well. It is this sudden increase in skin porosity or permeability that causes the warm feeling on your skin which is nothing to worry about and is entirely normal when using DMSO topically.

When you paint the DMSO and aloe vera onto your skin, make sure that this area is not sopping wet with DMSO +aloe vera. All you need is a thin damp layer painted onto the skin for best effect.

There is also no reason why you shouldn't use the DMSO in a sprayer. But please be aware that DMSO can dissolve some plastics. So if you're not sure then perhaps best to use a glass sprayer. So using colloidal silver and DMSO in a glass sprayer should be fine.

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Replied By Mrs. Hill (Arkansas, US) on 06/20/2014

Bill, Thank you for your time and response. I will try the silver and dmso together.
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Replied By Angelo (Boise, Id) on 02/01/2015

The warm feeling is actually a reaction with the water in your skin, not an increase in porosity. DMSO doesn't increase porosity or permeability; it simply dissolves a variety of compounds and is able to transport them quickly through your skin. It's nothing to worry about but it's the exact same thing you noticed when diluting it with water to a much lesser scale.
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Replied By Arum (Germany) on 04/18/2016

I understand that the reaction is with water, and that aloe vera contains more water than castor oil, hence the more intense reaction when using aloe vera.
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Replied By Rod (Portland, Oregon) on 05/22/2016

It is called "solvation." It is not, strictly speaking, a chemical reaction, as the molecules themselves are not altered--only their nearest-neighbor relationships change. The DMSO molecules like to be in contact with water molecules -- the total energy is lower, therefore potential energy is released as heat. The same thing happens when you mix salt with water, though the effect is too small to notice.
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Replied By Fred (Nicaragua) on 09/17/2016

The spray mechanism is made of plastic parts also, so I would be careful about the DMSO melting the actual sprayer pump/nozzle.
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Replied By Sean (Florida) on 07/07/2017

I have been working with dmso for years... read and studied clinical trials... sprayer is not a good idea!

Another note. Colloidal silver is not a cure all. It does have unique properties that will kill single cell organisms, bacterial or viral. Aids, cancer, herpes etc .... however it is very important to do your homework! Before you administer to your self or anyone else......

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