Replied By Lily (San Antonio, TX / U.S.A) on 09/30/2008
What is 5HTP? My grandmother suffers from Fibromyalgia, and I hate it. If there is something helpful, I would really like to know more. Please respond ASAp. Lily.
EC: More information here: https://www.earthclinic.com/supplements/FIVE-HTP.html
Replied By Bodulica (Barrie, CA) on 02/28/2015
I had very serious side effects with 5HTP: weakness, nausea heart fibrillation... For those sensitive to the increased level of the serotonin (serotonin syndrome, it is rare) - don't take it!Replied By carmel (Essex, England) on 01/08/2022
I have fibro and tried 5 htp, a dose of about 200 mg per night. To help with relaxation and sleep. I found the first day it helped, and the day after it made me feel less pain and more relaxed. But if I took it for two or three days in a row, I would feel rough/worse the second and third day.Replied By steve (MO) on 05/21/2023
The reason this occurs is that some people (ie me) have a SNP that prevents us from converting tryptophan into serotonin. We don't have the ability to convert tryptophan into 5-htp. 5-htp when given allows us to produce serotonin, and when we start feeling tired it is being converted from serotonin into melatonin the hormone required for us to sleep. I'm glad this worked