Acetyl-L-Carnitine for Peripheral Neuropathy

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Gord235 (Vancouver, British Columbia) on 01/01/2018:
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Update:

Since my last post I have learned that taking antibiotics can lower B12 levels and that a B12 insufficiency can be the cause of peripheral neuropathy in up to 7% of cases. I had surgery recently and was on antibiotics for two weeks. This may account for the dramatic improvement I experienced once I started taking a B12 supplement.

As a result of this new information I have returned to my regimen of taking B1- 2X100mg/daily, B6 - 2X100mg/daily, B12 - 2X5000mcg/daily as well as ALA - 4X200mg/daily and Serrapeptase - 10X120,000SU/daily. Although not completely rid of symptoms the frequency and intensity of pain has been reduced by 90%. I anticipate that I will eventually be able to reduce the number of things I am taking but feel certain that the B12 will be the last thing to go as it has been the only thing to give me overnight relief. I wish everyone well on their search for a cure.

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Gord235 (Vancouver, British Columbia) on 10/10/2017:
5 out of 5 stars

Update: I have been able to cut back on the B vitamins (1,6 and 50 complex) although I still take 2 X B12 5000mcg/day. I have increased the ALA (r+alpha lipoic acid) to 800mg/day as it seems to be helping the most.

I also take N-Acetyl-L-Carnite 1500mg/day and Calcium/Magnesium 2X 133/167mg/day.

This protocol has eliminated 90% of the pain and I believe it is the ALA that is helping the most. Best wishes and good luck to all in their search for relief.

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Brad (Owensboro, Ky) on 01/14/2012:
4 out of 5 stars

I am not saying anything conclusive yet, but I have been taking Acetyl-l-carnitine for three days. I had numbness, tingling and sometimes burning in my feet. I have been taking 800mg daily. After three day they feel remarkably better. I will post further as time goes on.

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Mike (New York City, New York) on 02/09/2009:
4 out of 5 stars

I have been taking Acetyl-L-Carnetine for a couple years to combat my peripheral neuropathy. It has been recommended by a neurologist in New York. My feet are progressively doing worse but I don't know how much worse they would be without it. I also take Alpha Lypoic Acid. I take about 3000mg of Acetyl-L-Carnetine a day. I am looking for whatever works. I have the neuropathy through anti-hiv meds and possible from the virus itself.
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