Hi Joyce, I had a kitty with mega colon. Although his vet termed it ideopathic, I believe it was due to spinal problems he had when we got him as a kitten. As he aged, he began experiencing occasional severe constipation, which became chronic. We had to do enemas for him at home, and sometimes take him in for more extensive procedures. Poor baby. Initially we tried pumpkin, then lactulose, and finally Cisipride. Though I prefer natural therapies for myself and my animals, the Cisipride finally made his life comfortable. It causes peristalsis in the colon and allows them to have a bowel movement. This drug was taken off the market for humans years ago due to it having some serious side effects. As I recall, the vets were somewhat reluctant to prescribe enough for our kitty's needs, and I was able to find it online from overseas. I do believe it made the last years of his life much more comfortable. All the best. PS If you do an enema at home (takes 2 people and is not at all easy), NEVER use a prepared enema solution, such as Fleet brand on a cat. It is deadly! We used warm water with a tiny bit of soap.