Estrogen can morph into neurotransmitters. So on some level you could say it is a neurotransmitter. As hormone levels drop neuropathy can occur. Neuropathy in women can start within a decade of approaching menopause. There are quite a few studies out on estriol and Parkinsons as well.
If you know a senior lady who suddenly developed some neurological condition who is trying to find some answers, a good question to ask is "Did you recently stop taking estrogen?" I know of several women who developed neuropathy after 30 years of estrogen therapy- just stopping. There are some natural safer ways to increase estrogen, I understand.
What helped me was a very small daily dose of natural thyroid (not the synthetic). I tested fine but my body temp was always around 96.8. Subclinical thyroid conditions do exist and if there is neuropahy it is worth researching as well. I did not know it would do this. I was just tired of wearing a winter coat at work and shivering in the desert.
If iron is low neuropathy can occur. My experience is that the homeopathic Carc Carb 6x or blackstrap molasses (huge section in this site) was real helpful. I used to go to a Dr. In Pa who demand that you take blackstrap molasses every day. If you did not he could tell.
Anyway it is worth doing a search on the following: "Estrogen Neuropathy" "Menopause Neuropathy" "Anemia Neuropathy" "Hypothyroidism Neuropathy" "Estriol Parkinsons" Estrogen Neurotransmitter"
Another thing that can help is searching "Dosha Test" If the body type is Vata neuropathy can occur. There are ways to make corrections to diet and sleeping schedule that can bring relief.