Last Modified on Feb 20, 2016
You’ve probably eaten a grape and enjoyed the soft burst of the ripe fruit in your mouth followed by the wave of cool, refreshing juice. But, did you realize that grapes, or at least the extract from grape seeds, deliver more benefits than just refreshment? Grape seed extract has a variety of health applications and benefits, which include improving cardiovascular function, reducing edema or swelling, improving wound healing, and others.
The History behind Grape Seed Extract
According to the National Center for Complementary and Alternative Medicine, grapes, including the leaves, have been used as a medical treatment since ancient Greek times. The tradition continues today as grape seed extract is a common folk remedy that is used to treat a variety of ailments. While the seeds used are taken from a variety of place, most of them actually are obtained from wine manufacturers.
The Major Health Benefits of Grape Seed
The extract of any fruit or seed considered the true essence of the fruit. The extract contains concentrated flavor as well as nutritional benefits. The same holds true with grape seed extract. This unique compound that is rendered from grape seeds and contains a rich combination of antioxidants and oligomeric proanthocyanidin complexes (OPCs). These nutritional components make grape seed extract effective for treating a variety of health conditions and supporting a number of health benefits including healing wounds, lowering cholesterol, treating atherosclerosis, improving circulation, enhancing cognitive function, and preventing cancer.
1. Healing Wounds
The antioxidants and vitamin E contained in grape seed extract promote cell regeneration. With this benefit, the extract promotes more rapid healing of wounds. A study published in the journal Free Radical Biology and Medicine supports this claim and provides evidence that the topical application of the extract supports dermal rejuvenation and healing.
2. Lowering Cholesterol
The active compounds in grape seed oil actually have a positive effect on the breakdown of fat. As your body is more capable of breaking down and eliminating fat and buildup in your cardiovascular system, your cholesterol levels will lower. A study shows that grape seed extract taken in conjunction with chromium has the greatest effect on lowering total and LDL or “bad” cholesterol levels.
3. Treating Atherosclerosis
Grape seed extract contains a high concentration of antioxidants. These components protect your blood vessels from damage and promote more effective blood circulation. The compound also helps break up plaque and other forms of buildup in your arteries.
4. Enhancing Cognitive Function
Grape seed extract is high in proanthocyanidins. These compounds actually help prevent cognitive decline and may actually boost your cognitive function. A study indicates that grape seed extract may be one of the most effective steps toward preventing cognitive loss due to aging.
5. Preventing Cancer
With the potency of antioxidants contained in grape seed extract, the natural compound has been shown to prevent the growth of several types of cancerous cells, including breast, stomach, colon, prostate, and lung, in test vials. However, research has been inconclusive whether the extract has the same effect in humans. One study has shown, though that the treatment is effective for treating skin cancer.
What the Experts Say
At present, experts have done a great deal of research on the effects of grape seed extract on the body. Studies show that the compounds found in the extract deliver a number of health benefits, including:
- A study showing the extract can relieve symptoms of venous insufficiency.
- Trials that the extract improves the strength of your blood vessels.
- A large randomized trial that shows the treatment is effective for reducing edema.
While some studies have shown positive results for using grape seed extract to treat a variety of conditions, others have been inconclusive. For example, a study promoted by the National Cancer Institute discovered that the extract did not prevent the hardening of breast tissue in conjunction with radiation treatment the way researchers would have expected. Nonetheless, the extract is accepted as an effective remedy and supplement for a variety of different health conditions.
How to Use Grape Seed Extract
Most people can tolerate the extract taken by mouth. The extract has been researched and found safe for use for up to 8 weeks in clinical trials. You can take grape seed as a dietary supplement in the form of capsules, tablets, or a liquid extract. Be sure to look for a product that contains 40 to 80% proanthocyanidins or an OPC content of at least 95%.
Continue reading below to find ways that our readers and contributors have used grape seed extract to benefit their health!
Remedies for Grape Seed Extract
The Popularity of Grape Seed Extract Remedies - Full List
|Grape Seed Extract Side Effects||0||2016-02-03|
[YEA] Well, Let me first say, I've had fibroids and ovarian cysts for over 7 years. They have progressively gotten worse and worse as far as heavy clotting periods, PMS, and weight gain. Basically my life revolves around my periods. I don't "do" western medicine so I only go to the doctor to find out what's going on. I'm also a vegetarian. My job is that of performer, so I've had to be meticulous about scheduling shows around my cycle. I'm so excited right now I had to share this immediately. It's early days, I'm only into day 4 of my period, but the change has been incredible. For a whole week before my period I did castor oil packs over where I consider the fibroids are. I rented movies, and spent every evening for about an hour and a half with the pack on my belly, and a heating pad over the area. Also, from the first day of my period I've been taking 2 (100mg) grapeseed extract tablets 3 times a day. They give me a bit of lose stool, but that's the least of my problems after all the bleeding I've endured over the years. Ok the report is: So far my bleeding has been cut in half, if not even more. A few very small clots, as apposed to huge clots. I feel different. I don't feel exhausted, and I'm thinking a miracle has happened to me. I don't know if it's the grape seed or the packs, but I am going to continue this procedure. I'm not sure how often I should do the packs, but I read in this forum that the grapeseed should be done only during your period to keep it's potency on your system. Oh, also something else. I had been taking BSM for over a year, (no decrease in bleeding, but other very good effects) and I read on this forum that House of Herbs had the most iron, so I orderd a whole case of it.. but the label is very sparse, and I think it might be sulfured, and that is not good because it thins the blood, so the only other thing I've changed is that I've cut OUT the sulfured BSM. I will update as I find out more, but right now I'm extremely happy. Day 4 and it's been a walk in the park!!!
Replied by Janice Gilliard
YEA (1) 100%Posted by Cortney (Albuquerque, NM) on 12/02/2008
[YEA] I recently moved to Albuquerque, NM from Colorado Springs, CO. I was working as a consultant and had to drive back. The morning I woke up, I had a lot of mucous in my throat and thought it would go away. An hour into my drive, it was still there. Two hours into my drive I started sneezing. After 6 hours of driving, I got to my mother's house in the Springs looking half dead and feeling absolutely terrible. I had cold symptoms. I was at the point that I knew if I went to bed, I would awake up feeling 20 times worse. My mother suggested "Grape Seed Extract" pills. She had gotten the idea from my sister who had found out about it the same way I had... word of mouth. It was 4pm when I took the first one. I was staying at a friends house and warned her I was getting sick. I forgot about the pill. At around 8pm, I wasn't sneezing and actually felt a little better. I took one before going to bed dreading my wake up. I can honestly say I woke up feeling great. I took three more that day as instructed on the bottle. Never got the symptoms again. This happened in September which is when I usually get that bad cold of the year. I have tried all the "cures" on here from the tomato tea to plain ACV, to hydrogen peroxide. Nothing ever worked like this has. Unbelievable really. I am testing my theory again with my son. He is almost 5 and is getting very sick. He took one tonight and I feel due to his age, I will keep it to one a day. We will see how he does in the morning.
I bought my bottle at whole foods though I imagine most health food stores carry it. Take 3 a day, 1 in the morning, afternoon and before bed. It's just a capsule, though my mother had solid pills. This was a life saver for me and I imagine if ACV doesn't work for all, this might. Literally took a few hours for me to feel better and more energized.
SIDE EFFECTS (2) 100%Posted by Paula (Montreal) on 02/03/2016
[SIDE EFFECTS] I started taking Grape Seed Extract recently and soon afterward began having anxiety (which is not usually a problem for me in the same situations I am currently in), heart palpitations that I thought would never end on some days and when there were no regular heart palpitations it felt like there was congestion or rumbling in my chest (similar to what I might have felt if I was congested with bronchitis).
I didn't link it to the Grape Seed Extract right away, but after a week or so I stopped taking it and within 36 hours I was back to how I usually feel. I waited a few days and took it again, and that day and into the next the symptoms were back so I won't be taking it anymore.
Posted by Sarah (Toledo, Ohio, United States) on 02/12/2013
[SIDE EFFECTS] I'm currently six months post partum and decided to start taking Grape Seed Extract for general health and younger looking skin. I was told to take 1mg for each pound I weigh (120lbs/120mg). The pills are 100mg each, so I was taking two a day with the understanding that excess would be excreted through urine. That day I started having heart palpitations, severe night sweats and anxiety/depression spells. This continued for two weeks (I thought it might be an adjustment period) before I reduced to one pill a day (100mg). The issues continued. I then stopped taking the GSE and all symptoms disappeared by the next day. I waited a week and tried it again. All negative symptoms came back in full force. In all my research on the internet, I'm not finding anyone with any issues like this regarding grape seed extract. I have two theories regarding my reaction and wanted to hear everyone else's feedback.
1. I'm thinking I might have post partum depression and the grape seed extract is amplifying it.
2. I had an epidural and petocin during my labor and my body is reacting poorly to all those drugs leaving my system.
These are merely guesses.
Age: 32, Weight: 120, good general health - no diagnosed issues, moderate exercise and a fairly healthy diet consisting of many fruits, vegetable, minimal meat and minimal processed foods. I do have alcoholic drinks almost every night (typically 1-3).
Replied by Rosanne
Replied by Sarah
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Replied by Kat
YEA (1) 100%Posted by crystal (any town, United States) on 04/23/2008
[YEA] I tried grapeseed extract for menstrual flooding associated with fibroids. I took 3 - 90 mg tablets 4 times a day and my menstrual was the closest to normal it's been in years. Also mother tried it for the same problem and was well pleased! I am happy!
Posted by Jim (Gary, Indiana Usa) on 02/05/2011
I recently saw a report about trials conducted on grapeseed extract and mrsa the trials were done in kuwait and it said that 43 strains of mrsa were killed by grapeseed extract. I do not know how many strains there are, but it seems like an easy enough test. If I had mrsa I would be taking grapeseed extract not to be confused with grapefruit seed extract. Also Jesus is the ultimate healer so pray when taking it. I would and do. Jim
Replied by Kat
YEA (1) 100%Posted by Al (Alvena, Sk., Canada) on 10/08/2012
[YEA] I am astonished that there is nothing on this website about grape seed extract. I was taking 9mg of hydro morph contin plus 900 mg of gabapentin four times per day for pain from peripheral neuropathy when I was told about grape seed extract (pycnogynol) and upon starting to use it at three doses of 50mg each per day I was able to reduce the other medications to two of each in three doses per day, a reduction of 50%, with a resulting lessening of the pain and numbness. On researching it I found that it is supposed to help any nerve pain, including arthritis, and helps ADD &ADHD symptoms. It also helps with behavior and attention problems in people with autism. My cousin used it for her autistic son and found that a dose of less than 1mg per pound of body weight was optimal as too much made her seven year old chatter non stop.
EC: Thanks, Al! A page on GSE is a terrific idea. Lots of enthusiasm out there about the natural health benefits of grapes and grape byproducts. Any other fans of this extract among ECers?
Replied by Elsaeasterly
Replied by Bess
Calgary, Alberta, Canada
YEA (2) 100%Posted by Michelle (San Anselmo, Ca) on 01/18/2012
[YEA] Grape Seed Extract for bladder infections -- Yes! Isn't it wonderful, and it's so much cheaper than D-Mannose and Doctors! I just posted about it on my blog. So glad to see others have tried it too.
Posted by Leriejane (Seattle, Wa, Usa) on 07/17/2010
[YEA] Grapeseed Extract cured my Urinary Tract Infection
I scheduled a doctor's visit for what I thought was a UTI (frequent urination with discomfort, bloated abdomen, back pain, etc) but they could not see me til the next week. So I bought grapeseed extract capsules and took 2 daily in conjunction with drinking water at every opportunity. (To help flush out any bacteria. )
The day before my appointment, my symptoms had stopped and I was never diagnosed with a UTI, though the doctor said my symptoms matched a UTI diagnosis, and that mine had probably cleared on its own. I didn't mention the grapeseed extract; I was just glad my symptoms were gone. It took about 5 days of grapeseed extract daily.
YEA (1) 100%Posted by Kitty (Rancho Cordova, Ca, USA) on 10/07/2012
Hi Casafina! Would u please tell us how much Grapeseed exract u r taking daily? Thank you for your time!
Posted by Kitty (Rancho Cordova, Ca, Usa) on 08/12/2012
Hi Andy! Can you please tell me how much of the Grape Seed Extract you have been taking? Once a day or more? In what form? Thanks kitty
Posted by Casafina (Sedona, Az) on 07/10/2012
Broken Capillaries on my nose for ever!!!! I just recently added Grape Seed Extract to my supplement list and it would appear to be working. I had first thought too much caffiene so I cut that out, then maybe I had a "booze" nose cut that out, then it was o still there must be years of sun damage. I had been covering with concealer and with in the first week of adding grapeseed extract I was able to go out with out any concealer. I take plenty of other supplements but my thinking is that it was the only thing that I had added after reading on here about it as a possible solution.
Posted by Afitch (Colorado Springs, Co, USA) on 06/07/2012
[YEA] I was diagnosed with small vessel capilaritis - red spots on my legs that look like pupura. They would appear almost on a daily basis and take a week to fully heal and fade away. I went to 12 doctors and no one could tell me what to do for them. I found an article on the internet that suggested that oligomeric procyanidins OPCs have shown to improve capillary vessel strength.
I have been taking grape seed extract supplements (from the local health food store) for about two years now and have virtually no capilaritis now. I want to share this with people because it seems that most doctors do not know of anything you can for this condition. These grape seed supplements have helped me greatly. Andy
YEA (1) 100%Posted by Alice (Jacksonville, Fl) on 04/28/2008
[YEA] Grape seed extract cream from heath store is great for wrinkles.